Analyze Repeated Measures Studies Using Bayesian Techniques Going beyond standard non-Bayesian books, Bayesian Methods for Repeated Measures presents the main ideas for the analysis of repeated measures and associated designs from a Bayesian viewpoint. It describes many inferential methods for analyzing repeated measures in various scientific areas, especially biostatistics. The author takes a practical approach to the analysis of repeated measures. He bases all the computing and analysis on the WinBUGS package, which provides readers with a platform that efficiently uses prior information. The book includes the WinBUGS code needed to implement posterior analysis and offers the code for download online. Accessible to both graduate students in statistics and consulting statisticians, the book introduces Bayesian regression techniques, preliminary concepts and techniques fundamental to the analysis of repeated measures, and the most important topic for repeated measures studies: linear models. It presents an in-depth explanation of estimating the mean profile for repeated measures studies, discusses choosing and estimating the covariance structure of the response, and expands the representation of a repeated measure to general mixed linear models. The author also explains the Bayesian analysis of categorical response data in a repeated measures study, Bayesian analysis for repeated measures when the mean profile is nonlinear, and a Bayesian approach to missing values in the response variable.
Introduction to the Analysis of Repeated Measures Introduction Bayesian Inference Bayes's Theorem Prior Information Posterior Information Posterior Inference Estimation Testing Hypotheses Predictive Inference The Binomial Forecasting from a Normal Population Checking Model Assumptions Sampling from an Exponential, but Assuming a Normal Population Poisson Population Measuring Tumor Size Testing the Multinomial Assumption Computing Example of a Cross-Sectional Study Markov Chain Monte Carlo Metropolis Algorithm Gibbs Sampling Common Mean of Normal Populations An Example Additional Comments about Bayesian Inference WinBUGS Preview Exercises Review of Bayesian Regression Methods Introduction Logistic Regression Linear Regression Models Weighted Regression Nonlinear Regression Repeated Measures Model Remarks about Review of Regression Exercises Foundation and Preliminary Concepts Introduction An Example Notation Descriptive Statistics Graphics Sources of Variation Bayesian Inference Summary Statistics Another Example Basic Ideas for Categorical Variables Summary Exercises Linear Models for Repeated Measures and Bayesian Inference Introduction Notation for Linear Models Modeling the Mean Modeling the Covariance Matrix Historical Approaches Bayesian Inference Another Example Summary and Conclusions Exercises Estimating the Mean Profile of Repeated Measures Introduction Polynomials for Fitting the Mean Profile Modeling the Mean Profile for Discrete Observations Examples Conclusions and Summary Exercises Correlation Patterns for Repeated Measures Introduction Patterns for Correlation Matrices Choosing a Pattern for the Covariance Matrix More Examples Comments and Conclusions Exercises General Mixed Linear Model Introduction and Definition of the Model Interpretation of the Model General Linear Mixed Model Notation Pattern of the Covariance Matrix Bayesian Approach Examples Diagnostic Procedures for Repeated Measures Comments and Conclusions Exercises Repeated Measures for Categorical Data Introduction to the Bayesian Analysis with a Dirichlet Posterior Distribution Bayesian GEE Generalized Mixed Linear Models for Categorical Data Comments and Conclusions Exercises Nonlinear Models and Repeated Measures Nonlinear Models and a Continuous Response Nonlinear Repeated Measures with Categorical Data Comments and Conclusion Exercises Bayesian Techniques for Missing Data Introduction Missing Data and Linear Models of Repeated Measures Missing Data and Categorical Repeated Measures Comments and Conclusions Exercises References